Aggressive Blood Pressure control cuts the cardiac Risk in patients with prediabetes

Treatment of systolic hypertension to a level of 120 mm Hg in place of 140 mm Hg significantly decreased the rate of cardiovascular events in the patients with prediabetes, according to a recent analysis of a multicenter, randomized, controlled, open-label Systolic Blood Pressure Intervention Trial.

That is why, prediabetes did not undercut the cardiovascular benefits of agressive systolic blood pressure (SBP) control in elderly, high-risk, hypertensive patients, Adam P. Bress, PharmD, MS, and his team mates concluded in a presentation at the yearly scientific session of the American Diabetes Association.

Physicians continue to discuss optimal SBP values, especially in subjects with diabetes or prediabetes. SPRINT, that was conducted at 102 clinical centers in the United States of America, randomly chose adults aged fifty years or older who were at high risk of cardiac disease and average  BPs of 130 to 180 mm Hg to antihypertensive medication targeted to less than 140 mm Hg  or less than 120 mm Hg . The primary endpoint was a composite of Acute myocardial infarction, acute coronary syndrome without AMI , stroke, acute decompensated heart failure, and acute cardiovascular death.

Dr Jitesh Arora
Cardiology Consultant